In 1501, Rodrigo de Bastidas was the first European to explore the Isthmus of Panama sailing along the eastern coast. A year later Christopher Columbus, sailing south and eastward from upper Central America, explored Bocas del Toro, Veragua, the Chagres River and Porto Belo (Beautiful Port) which he named. Soon Spanish expeditions would converge upon Tierra Firma (also Tierra Firme, Spanish from the Latin terra firma, "dry land" or "mainland") which served in Spanish colonial times as the name for the Isthmus of Panama
In 1509, authority was granted to Alonso de Ojeda and Diego de Nicuesa to colonize the territories between the west side of the Gulf of Uraba to Cabo Gracias a Dios in present-day Honduras. The idea was to create an early unitary administrative organization similar to what later became Nueva España (now Mexico). Tierra Firme later received control over other territories: the Isla de Santiago (now Jamaica) the Cayman Islands; Roncador, Quitasueño, and Providencia and other islands now under Colombian control.